Events The 11th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 11th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2007

Citation

Maria J. G. Fernandes, M. Sameiro T. Gonçalves, Susana P. G. Costa, Fused Oxopyrans as Fluorescent Labels for Neurotransmitter Amino Acids, in Proceedings of The 11th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2007, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-11-01312

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Fused Oxopyrans as Fluorescent Labels for Neurotransmitter Amino Acids

Maria J. G. Fernandes ¹

M. Sameiro T. Gonçalves ¹

Susana P. G. Costa ¹

1. Centro de Química, Universidade do Minho, Gualtar, 4710-057 Braga, Portugal

Abstract

Fluorescent conjugates of N-benzyloxycarbonyl protected γ-aminobutyric acid (GABA) were prepared by coupling to its C-terminus several polyheteroaromatic labels, based on the pyran ring. Photophysical properties were evaluated and the results showed that these GABA conjugates presented strong fluorescence with maximum emission wavelengths between 393 and 503 nm, as well as high fluorescence quantum yields in ethanol.

Keywords

Fluorescent labelling

Benzopyrans

Neurotransmitter amino acids

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