Events 8th International Electronic Conference on Medicinal Chemistry

Event submissions

Published

10.3390/ECMC2022-13241

This submission belongs to the session S4. Small molecules as drug candidates of the event 8th International Electronic Conference on Medicinal Chemistry

Published date

01 Nov, 2022

Academic Editor

Alfredo Berzal-Herranz

Citation

Azizah Malebari, Shu Wang, Mary J Meegan, Synthesis and Biological Evaluation of Novel 3-Isopropenyl-β-lactams: Heterocyclic Bridged Analogues of Combretastatin A-4 as Novel Antimitotic Agents in Breast Cancer, in Proceedings of 8th International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ECMC2022-13241

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Synthesis and Biological Evaluation of Novel 3-Isopropenyl-β-lactams: Heterocyclic Bridged Analogues of Combretastatin A-4 as Novel Antimitotic Agents in Breast Cancer

Azizah Malebari ¹

Shu Wang ²

Mary J Meegan ²

1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Abdulaziz University, Jeddah, KSA School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, 152-160 Pearse Street, Trinity College Dublin, Dublin 2, Ireland

2. School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Trinity Biomedical Sciences Institute, 152-160 Pearse Street, Dublin 2 DO2R590, Ireland.

Abstract

Keywords

Combretastatin A-4

MCF-7 cells

β-lactams (2-azetidinones)

Antimitotic Agents

Poster

sciforum-065899.pdf