Events The 11th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 11th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2007

Citation

I. Aldana, S. Pérez-Silanes, B. Solano, A. Burguete, R. Villar, E. Vicente, A. Monge, Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives, in Proceedings of The 11th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2007, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-11-01332

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Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives

I. Aldana ¹

S. Pérez-Silanes ¹

B. Solano ¹

A. Burguete ¹

R. Villar ¹

E. Vicente ¹

A. Monge ¹

1. Unidad en Investigación y Desarrollo de Medicamentos, Centro de Investigación en Farmacobiología Aplicada (CIFA), University of Navarra, 31080 Pamplona, Spain.

Abstract

The unexpected substitution of fluorine atoms and phenoxy groups linked to quinoxaline or benzofuroxan rings is described. The synthesis of 2-benzyl and 2-phenoxy3-methylquinoxaline 1,4-di-N-oxide derivatives was based on the classical Beirut reaction. The experimental conditions (reaction solvent and catalyst) were explored with the aim of obtaining the target compounds.

Keywords

n/a

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