Events The 11th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 11th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2007

Citation

David Malinák, M. Walko, J. Gonda, Synthesis and Properties of New Nucleobase Containing Amphiphiles and bola-amphiphilesclick to see Communication, in Proceedings of The 11th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2007, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-11-01339

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Synthesis and Properties of New Nucleobase Containing Amphiphiles and bola-amphiphilesclick to see Communication

David Malinák ¹

M. Walko ¹

J. Gonda ¹

1. Department of Organic Chemistry, Institute of Chemistry, Faculty of Science, P.J. Šafárik University, Moyzesova 11., 040 01, Košice, Slovak Republic

Abstract

We present here synthesis and properties of new amphiphiles and homoditopical bolaamphiphiles, containing nucleobases. This amphiphilic and bolaamphiphilic compounds were prepared by the addition of the amino group to the isothiocyano group attached to a nucleobase. This compounds are capable of creating several non-covalent interactions, especially the hydrogen bonds resulting in formation of agregates.

Keywords

Nucleobases

Amphiphiles

Bolaamphiphiles

Thiourea

Photocleavage Studies of γ-aminobutyric acid (GABA) Conjugates

Substituted pyrazine-2,5-dicarboxamides: Synthesis, Hydrophobicity Parameters, and Antimycobacterial Evaluation