Events 8th International Electronic Conference on Medicinal Chemistry

Event submissions

Published

10.3390/ECMC2022-13423 (registering DOI)

This submission belongs to the session S3. General of the event 8th International Electronic Conference on Medicinal Chemistry

Published date

01 Nov, 2022

Academic Editor

Alfredo Berzal-Herranz

Citation

Silvana Alfei, Alessia Zorzoli, Danilo Marinpietri, Debora Caviglia, Chiara Brullo, Gian Carlo Schito, Anna Maria Schito, Enhanced Antibacterial Activity of a Cationic Copolymer by its Complexation with a Weakly Active Pyrazole Derivative, in Proceedings of 8th International Electronic Conference on Medicinal Chemistry, 1 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ECMC2022-13423

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Enhanced Antibacterial Activity of a Cationic Copolymer by its Complexation with a Weakly Active Pyrazole Derivative

Silvana Alfei ¹

Debora Caviglia ²

Alessia Zorzoli ³

Danilo Marinpietri ³

Chiara Brullo ⁴

Gian Carlo Schito ⁵

Anna Maria Schito ²

1. Department of Pharmacy University of Genoa, Viale Cembrano 4, 16148, Genova, Italy

2. Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16132 Genoa, Italy

3. Cell Factory, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy

4. Department of Pharmacy University of Genoa, Viale Benedetto XV, Genova, Italy

5. Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa

Abstract

Keywords

pyrazole compounds

CB1H-loaded copolymer NPs

Gram-positive and Gram-negative MDR isolates

MICs and MBCs

time-kill experiments

cytotoxicity on human cells

selectivity index

Poster

Alfei_Genova-1.pdf