EventsThe 26th International Electronic Conference on Synthetic Organic Chemistry
Published
with-doi10.3390/ecsoc-26-13546 (registering DOI)
This submission belongs to the session S1. General Organic Synthesis of the event The 26th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2022
Academic Editor
author-avatarJulio A. Seijas
Citation
Fatima BELHADJ, Zahira KIBOU, Julio A Seijas, María Pilar Vázquez-Tato, Nourreddine CHOUKCHOU-BRAHAM, Highly Efficient Approach to the Synthesis of New Chromeno[2,3-d] Pyrimidine derivatives, in Proceedings of The 26th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-26-13546
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Highly Efficient Approach to the Synthesis of New Chromeno[2,3-d] Pyrimidine derivatives

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Nourreddine CHOUKCHOU-BRAHAM 5
1. 1) Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie 3)Université d’Oran 1, Faculté de Médecine, B.P.1510, 31000 ELMENAOUAR Oran, Algérie
2. 1) Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen, Algérie 2) Université d’Ain Témouchent, Faculté des Sciences et de la technologie, BP 284, 46000 Ain Témouchent, Algérie
3. 4) Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Santiago de Compostela, A da, Alfonso X El Sabio s/n, 27002 Lugo, Spain
4. 4)Departamento de QuímicaOrgánica, Facultad de Ciencias, Universidad de Santiago de Compostela, A da, Alfonso X El Sabio s/n, 27002 Lugo, Spain
5. 1)Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119,13000 Tlemcen
Abstract

5H-chromeno[2,3-d]pyrimidines constitute an important class of heterocyclic compounds having diverse biological activities such as antifungal, anti-tumor, antibacterial, antihypertensive activities. In the continuation of our research aimed at developing new methods for the preparation of new heterocyclic compounds, we present in this work, a simple, efficient, and environmentally approach for the synthesis of new and functionalized chromeno[2,3-d]pyrimidines derivatives by the treatment of 2-amino-3-cyano-4H-chromenes with anhydride acetic under solvent-free conditions

Keywords
5H-chroméno[2,3-d]pyrimidines
2-amino-3-cyano-4H-chromene
Solvent-free conditions.
Manuscript
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