Events The 26th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-26-13570 (registering DOI)

This submission belongs to the session S1. General Organic Synthesis of the event The 26th International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2022

Academic Editor

Julio A. Seijas

Citation

Sandra Cecilia Ramírez López, María del Rocio Gámez Montaño, Alejandro Corona-Díaz, Manuel Alejandro Rentería-Gómez, Shirikant G. Pharande, A green isocyanide based multicomponent click reactions for the synthesis of 1-substituted 1H-1,2,3,4-tetrazoles, in Proceedings of The 26th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-26-13570

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A green isocyanide based multicomponent click reactions for the synthesis of 1-substituted 1H-1,2,3,4-tetrazoles

Sandra Cecilia Ramírez López ¹

María del Rocio Gámez Montaño ¹

Alejandro Corona-Díaz ¹

Manuel Alejandro Rentería-Gómez ¹

Shirikant G. Pharande ¹

1. Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Departamento de Química

Abstract

A series of five 1-substituted-1H-1,2,3,4-tetrazoles were synthesized via a novel isocyanide based multicomponent click reaction (IMCCR) under solvent, catalyst and column-free conditions at room temperature. This new, green and sustainable IMCCR methodology resulted in good to excellent yields(76–88%).

Keywords

green synthesis

1-substituted 1H-1,2,3,4-tetrazoles

isocyanide-based multicomponent reactions (I-MCR).

Manuscript

sciforum_066798_original_sciforum_066798_SCRL.pdf

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