This submission belongs to the session f. Supramolecular Chemistry of the event The 11th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Nov, 2007
Citation
Mercedes Novo, Wajih Al-Soufi, Fluorescence Study of the Supramolecular Interactions between Coumarins and Serum Albumin, in Proceedings of The 11th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2007, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-11-01358
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Fluorescence Study of the Supramolecular Interactions between Coumarins and Serum Albumin
Mercedes Novo 1
Wajih Al-Soufi 1
1. Dpto. Química Física, Facultade de Ciencias, Universidade de Santiago de Compostela, E-27001 Lugo, Spain
Abstract
In this work we study the supramolecular interactions between fluorescent dyes of the family of aminocoumarins and a protein which is the main responsible for matter transport in blood, the serum albumin. The experimental data obtained by fluorescent titrations are analysed using Principal Components Global Analysis to obtain the equilibrium binding constants and the fluorescence spectra of the dyes bound to the protein. The results obtained for the different aminocoumarins are then compared.
Keywords
n/a
Host-Guest Supramolecular Dendrimers
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