EventsThe 26th International Electronic Conference on Synthetic Organic Chemistry
Published
with-doi10.3390/ecsoc-26-13646 (registering DOI)
This submission belongs to the session S1. General Organic Synthesis of the event The 26th International Electronic Conference on Synthetic Organic Chemistry
Published date
16 Nov, 2022
Academic Editor
author-avatarJulio A. Seijas
Citation
Jovana Muškinja, Zoran Ratković, Chalcone analogues as substrates in the synthesis of some N-acyl pyrazolines, in Proceedings of The 26th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2022, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-26-13646
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Chalcone analogues as substrates in the synthesis of some N-acyl pyrazolines

Zoran Ratković 2
1. Department of Sciences, Institute for Information Technologies, University of Kragujevac, Jovana Cvijića bb, 34000 Kragujevac, Serbia
2. Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia
Abstract

Heterocyclic compounds are one of the most important organic compounds, that frequently present as active pharmaceuticals products. Among them, nitrogen-containing heterocycles have attracted much interest from various researchers due to their wide range of biological activities. Considering the importance of all these characteristics and the very pronounced application, and as a continuation of our work on pyrazolines, this paper shows the synthesis of some new N-acyl pyrazolines in very good yields. These products were obtained by reacting chalcone analogues with hydrazine in the presence of boiling formic or acetic acid.

Keywords
chalcone analogues
heterocycle
pyrazolines
Manuscript
Chemo selective protection of aldehydes functional group catalyzed by MOFs
Transition metal-catalyzed, “ligand free” P–C coupling reactions under MW conditions