Development of easy and practical access of novel imidazo[2,1-b]thiazole derivatives

The scientific discoveries exposed the privileged skeleton of the imidazo[2,1‐b]thiazole heterocycles for the development of pharmacological compounds. Imidazo[2,1‐b]thiazoles showed interesting potency against a bord range of biological activities such as antibacterial, antifungal, antiviral, anti‐ inflammatory, antihypertensive, anticancer and antioxidant, also used as drug that has significant immunomodulatory properties (Levamisole). Encouraged by these bioactivities, we report herein a new easy and efficient procedure for the preparation of imidazo[2,1-b]thiazole derivatives under green chemistry conditions.