Events The 10th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 10th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2006

Citation

Giang Vo-Thanh, Didier Gori, Olivier Nguyen Van Buu, Bruce Pégot, Asymmetric aza-Diels-Alder reaction of Danishefsky’s diene with imines in a chiral reaction medium, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01378

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Asymmetric aza-Diels-Alder reaction of Danishefsky’s diene with imines in a chiral reaction medium

Bruce Pégot ¹

Olivier Nguyen Van Buu ¹

Didier Gori ¹

Giang Vo-Thanh ¹

1. Laboratoire de Chimie des Procédés et Substances Naturelles, ICMMO, CNRS UMR 8182, Université Paris-Sud, 91405 Orsay Cedex, France

Abstract

The asymmetric aza-Diels-Alder reaction of chiral imines with Danishefsky’s diene in chiral ionic liquids provides the corresponding cycloadduct with moderate to high diastereoselectivity. The reaction has proved to perform better at room temperature in ionic liquids without either Lewis acid catalyst or organic solvent. Chiral ionic liquids are recycled while their efficiency is preserved.

Keywords

n/a

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