Events The 10th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 10th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2006

Citation

P. Seck, G. Kirsch, D. Thomae, Synthesis of Thiophene Analogues of the Tacrine Series, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01380

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Synthesis of Thiophene Analogues of the Tacrine Series

D. Thomae ¹

G. Kirsch ¹

P. Seck ²

1. Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, UFR Sci FA Université Paul Verlaine-METZ, 1 Bld Arago, F-57070 METZ, France

2. Laboratoire de Chimie, Faculté des Sciences, de la Technologie et de la Communication Université Luxembourg 162a, avenue de la Faïencerie, L-1511 Luxembourg, Grand-Duché de Luxembourg

Abstract

Substitued 3-amino-2-cyanothiophenes condensed with cyclic ketones afforded in 2 or 3 steps analogues of velnacrine. Condensation under Friedländer conditions gave Tacine analogues in one step.

Keywords

n/a

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