EventsThe 10th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-10-01383
This submission belongs to the session a. General Organic Synthesis of the event The 10th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Nov, 2006
Citation
Anton V. Dolzhenko, Anna V. Dolzhenko, Wai-Keung Chui, Reaction of azaheterylguanidines with trichloroacetonitrile, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01383
Share
Email
Facebook
Twitter
LinkedIn

Reaction of azaheterylguanidines with trichloroacetonitrile

Anton V. Dolzhenko 1
Anna V. Dolzhenko 1
Wai-Keung Chui 1
1. Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
Abstract
Separate reaction of benzimidazolyl-2-guanidine and benzothiazolyl-2-guanidines with trichloroacetonitrile was investigated. 2,4-Diamino[1,3,5]triazino[1,2-a]benzimidazole and 2,4-diimino[1,3,5]triazino[2,1-a][1,3]benzothiazoles were found to be products of the reaction. The structures of the compounds obtained were established using 1H NMR spectroscopy.
Keywords
triazines
benzimidazoles
benzothiazoles
guanidines
cyclization
Reaction of 2-guanidino-4-quinazolinone with arylaldehydes
Synthesis of novel benzoannelated eight-membered heterocycles: easy access to benzo[f][1,4]oxazocin-1-ones