EventsThe 10th International Electronic Conference on Synthetic Organic Chemistry
Published
This submission belongs to the session a. General Organic Synthesis of the event The 10th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Nov, 2006
Citation
Jeanne-Marie Begouin, Stéphanie Hesse, Synthesis of novel benzoannelated eight-membered heterocycles: easy access to benzo[f][1,4]oxazocin-1-ones, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01384
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Synthesis of novel benzoannelated eight-membered heterocycles: easy access to benzo[f][1,4]oxazocin-1-ones

Jeanne-Marie Begouin 1
Stéphanie Hesse 1
1. Laboratoire d’Ingénierie Moléculaire et Biochimie Pharmacologique, Université Paul Verlaine - Metz, 1 Boulevard Arago, 57070 METZ, France
Abstract
Medium-sized N-heterocycles, in particular eight-membered azocines, are key structures occurring in many natural products and in some compounds having biological activities. We described here an easy access to benzo[f][1,4]oxazocin-1-ones starting from 2-acetylbenzoic acid.
Keywords
eight-membered N
O heterocycles
ethanolamines
ZnCl<sub>2</sub>
Reaction of azaheterylguanidines with trichloroacetonitrile
Synthesis of Cyclic Enehydrazides by Ring-Closure Metathesis. Application to the Enantioselective Synthesis of 2-Alkyl and Aryl Piperidines