EventsMOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Event submissions
Published
with-doi10.3390/mol2net-09-14116 (registering DOI)
This submission belongs to the session 02. CHEMBIO.MOL-09: Org. Chem., Med. Chem., Mol. Biol., & Pharm. Industry Congress, Paris, France-Fargo, USA, 2023. of the event MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Published date
05 Mar, 2023
Academic Editor
author-avatarHumbert G. Díaz
Citation
Jessica P De Moura, Teresa CML Rodrigues, Igor MA De Araujo, Nikole D Trigueiro, Paulo SDS Pereira, Jeremias J Emídio, Marcus Tullius Scotti, Luciana Scotti, Alex France Messias Monteiro, Retinoic acid isomers as promising molecules against Alzheimer's disease, in Proceedings of MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed., 25 December–31 December 2023, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-09-14116
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Retinoic acid isomers as promising molecules against Alzheimer's disease

Jessica P De Moura 1
Teresa CML Rodrigues 1
Igor MA De Araujo 1
Nikole D Trigueiro 1
Paulo SDS Pereira 1
Jeremias J Emídio 1
Marcus Tullius Scotti 1
Luciana Scotti 1,2
Alex France Messias Monteiro 1
1. Postgraduate Program in Bioactive Natural and Synthetic Products, Federal University of Paraíba, Castelo Branco - João Pessoa - Brazil
2. Teaching and Research Management - University Hospital, Federal University of Paraíba, João Pessoa, PB, Brazil
Abstract

Alzheimer's is a neurodegenerative and
irreversible disease. In Alzheimer's disease, it is
possible to identify the presence of insoluble
amyloid β deposits in plaques in the brain.
Retinoic acid isomers are being studied as a new
alternative for Alzheimer's disease. In this work,
the isomers are analyzed: all-trans retinoic acid,
9-cis retinoic acid and 13-cis retinoic acid. They
may play an important role in AD by protecting
neurons from β-amyloid-induced cell death.

Keywords
Chemical
pharmacochemistry
chemoinformatics
Manuscript
jessica-jessicapaivascc@gmail.com.pdf
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