EventsMOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Event submissions
Published
with-doi10.3390/mol2net-09-14117 (registering DOI)
This submission belongs to the session 02. CHEMBIO.MOL-09: Org. Chem., Med. Chem., Mol. Biol., & Pharm. Industry Congress, Paris, France-Fargo, USA, 2023. of the event MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Published date
05 Mar, 2023
Academic Editor
author-avatarHumbert G. Díaz
Citation
Jeremias J Emídio, Paulo SDS Pereira, Igor MA De Araujo, Jessica P De Moura, Teresa CML Rodrigues, Nikole D Trigueiro, Luciana Scotti, Alex France Messias Monteiro, Stereochemical implications of remdesivir in combating the COVID-19, in Proceedings of MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed., 25 December–31 December 2023, MDPI: Basel, Switzerland, doi: 10.3390/mol2net-09-14117
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Stereochemical implications of remdesivir in combating the COVID-19

Jeremias J Emídio 1
Paulo SDS Pereira 1
Igor MA De Araujo 1
Jessica P De Moura 1
Teresa CML Rodrigues 1
Nikole D Trigueiro 1
Luciana Scotti 1,2
Alex France Messias Monteiro 1
1. Postgraduate Program in Bioactive Natural and Synthetic Products, Federal University of Paraíba, Castelo Branco - João Pessoa - Brazil
2. Teaching and Research Management - University Hospital, Federal University of Paraíba, João Pessoa, PB, Brazil
Abstract

The covid-19 is an infectious disease of the repertory tract caused by beta coronavirus, a disease that was considered a pandemic by the World Health Organization (WHO) in March 2020. Currently several vaccines are available for the prevention of covid-19, however few drugs have been shown to be effective in combating the current coronavirus, with remdesivir being the only approved drug Food and Drug Administratio (FDA). The remdesivir has two diastereoisomers due to the presence of a chiral phosphorous atom in its molecule, and the diastereomer-(Sp) is used in the clinic.

Keywords
Chemical
pharmacochemistry
chemoinformatics
Manuscript
jeremias.pdf
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