EventsThe 10th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-10-01415
This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 10th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Nov, 2006
Citation
Ulrich Jordis Jordis, Behrooz H. Yousef, New Synthesis of 4,4'-Diethylaminoethoxyhexestrol dihydrochloride (Coralgil) and scaling up to multi-grams scale, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01415
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New Synthesis of 4,4'-Diethylaminoethoxyhexestrol dihydrochloride (Coralgil) and scaling up to multi-grams scale

Behrooz H. Yousef 1
Ulrich Jordis Jordis 1
1. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Austria
Abstract
We report here new preparation with significant yield improvement of title compound. For this purpose the preparation of 4,4'-diethylaminoethoxyhexestrol dihydrochloride under different reported and analogue conditions have been tried. The optimized synthesis of Coralgil is reported. The synthesis was also scaled up to multi-grams for chemo-genomics study.
Keywords
n/a
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