Events The 10th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 10th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2006

Citation

Georges J. Hoornaert, Frans Compernolle, Wim M. De Borggraeve, Jo Alen, Evaluation of the ß-turn inducing properties of an achiral analogue of aminopiperidinone carboxylates, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01429

Facebook

Twitter

Evaluation of the ß-turn inducing properties of an achiral analogue of aminopiperidinone carboxylates

Jo Alen ¹

Wim M. De Borggraeve ¹

Frans Compernolle ¹

Georges J. Hoornaert ¹

1. Molecular Design & Synthesis, Department of Chemistry, K.U.Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium

Abstract

cis-4-(Acetylamino)-N-methylcyclohexane carboxamide has been selected as all carbon ring analogue of the previously described 5-aminopiperidinone-2-carboxylate systems. The potential ß-turn inducing properties of this model compound are evaluated by means of NMR analysis and molecular modeling.

Keywords

ß-turn mimic

intramolecular hydrogen bridge

achiral

aminopiperidinone carboxylate

Antimicrobial evaluation of benzo[a]phenoxazine heterocycles: structure–activity relationships

NMR Properties of SePPh₃ in the Solid State