Drug interactions, common problems in clinical practice, are one of the leading causes of adverse drug events, including toxicity or adverse reactions during use, failure to treatment, and can even lead to death. The combination of drugs is inevitable, especially in the case of multiple diseases, multiple symptoms. In most cases, physicians actively combine drugs to maximize effectiveness and minimize side effects, or in some cases combine drugs after carefully weighing benefits and risks. ten]. However, adverse drug interactions can be prevented by special precautions or by taking interventions to reduce the risk. Therefore, in order to give appropriate warnings to help doctors weigh the benefits/risks of drug combinations, the research team assessed the current situation of drug-drug interactions at the Department of Medical Examination traditional - the Ministry of Public Security from which to make recommendations and attention in prescribing practices at hospitals.