Events The 10th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session e. Symposium on Microwave Assisted Synthesis of the event The 10th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2006

Citation

Alžbeta Krutošíková, Katarína Kráľová, Daniel Zbojek, Martin Moncman, Renata Gašparová, Microwave-assisted Reactions of Substituted furo[3,2-b]pyrrole-5-carboxhydrazides and their Biological Activity, in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01436

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Microwave-assisted Reactions of Substituted furo[3,2-b]pyrrole-5-carboxhydrazides and their Biological Activity

Alžbeta Krutošíková ¹

Katarína Kráľová ²

Daniel Zbojek ¹

Martin Moncman ¹

Renata Gašparová ¹

1. Department of Chemistry, Faculty of Natural Sciences, University of St. Cyril and Methodius, Námestie Jozefa Herdu 2, Sk-917 01 Trnava, Slovakia

2. Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-2,

Abstract

The microwave-assisted reactions of substituted furo[3,2-b]pyrrole-5-carboxhydrazides 1 with 5-substituted furan-2-carboxaldehydes 2, thiophene-2-carboxaldehyde 3 and 2-formyl-4-methylfuro[3,2-b]pyrrole-5-carboxylate 4 have been studied under microwave irradiation. Reactions of 1 with 4-substituted 1,3-oxazol-5(4H)-ones 8 led to imidazole derivatives 9. The effects of hydrazones 5-7 on inhibition of photosynthetic electron transport in spinach chloroplasts were investigated.

Keywords

furo[3,2-b]pyrrole-5-carboxhydrazide

furan-2-carboxaldehyde

thiophene-2-carboxaldehyde

2-formyl-4-methylfuro[3,2-b]pyrrole-5-carboxylate

microwave irradiation

Microwave Assisted Oxidation of Organic Substrates Using Tetramethylammonium fluorochromate (TMAFC)

(4-Isobutyl-phenyl)-acetic acid (Ibufenac) Microwave-Assisted and Conventional Synthesis