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In this work, we study the Cauchy problem of the 3d-Anisotropic Boussinesq system with Horizontal dissipation and stratification effect for axisymmetric data. This system couples the Navier-stokes equation with a non-homogenous transport-diffusion equation. More precisely, we prove that this kind of system admits a unique global solution belongs to the Anisotropic Sobolev spaces.