This submission belongs to the session f. Supramolecular Chemistry of the event The 10th International Electronic Conference on Synthetic Organic Chemistry
Published date
30 Nov, 2006
Citation
Victor Hugo Soto Tellini, Francisco Meijide, Aida Jover, Luciano Galantini, Juan V. Trillo Novo, José Vázquez Tato, Synthesis, characterization and self aggregation of a new neo-pentylamide cholic derivative (Na-n-penC), in Proceedings of The 10th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2006, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-10-01446
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Synthesis, characterization and self aggregation of a new neo-pentylamide cholic derivative (Na-n-penC)
Victor Hugo Soto Tellini 1
Francisco Meijide 1
Aida Jover 1
Luciano Galantini 2
Juan V. Trillo Novo 1
José Vázquez Tato 1
1. Universidad de Santiago de Compostela, Facultad de Ciencias, Avda. Alfonso X El Sabio s/n, 27002 Lugo, Spain
2. Dipartimento di Chimica and Research Center SOFT-INFM-CNR, Università di Roma “La Sapienza”, P. le A. Moro 5, 00185 Roma, Italy
Abstract
The self-aggregation in aqueous solution of a new neo-pentyl amide of the 3-β-amino derivative of cholic acid (Na-n-penC) has been investigated in aqueous solution by surface tension and steady state-fluorescence spectroscopy of pyrene (used as a probe). The nature of the agregates was determined by transmission electron microscopy (TEM) revealing that vesicles are formed. The structure of the compound in the solid state was resolved by X-ray spectroscopy. The synthesis of the compound is also given.
Keywords
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