Events The 2nd International Electronic Conference on Toxins

Event submissions

Published

This submission belongs to the session S3. Use of toxins as tools for research, drug discovery, and therapeutics of the event The 2nd International Electronic Conference on Toxins

Published date

14 Jul, 2023

Academic Editor

Cesare Montecucco

Citation

Kristina R. Denisova, Alexey V. Feofanov, Nikita A. Orlov, Oksana V. Nekrasova, Properties of Atto488-Agitoxin 2 As a Fluorescent Ligand of Kv1.3 Сhannel, in Proceedings of The 2nd International Electronic Conference on Toxins, 14 July–28 July 2023, MDPI: Basel, Switzerland

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Properties of Atto488-Agitoxin 2 As a Fluorescent Ligand of Kv1.3 Сhannel

Kristina R. Denisova ^1,2

Nikita A. Orlov ^1,2

Alexey V. Feofanov ^1,2

Oksana V. Nekrasova ¹

1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia

2. Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia

Abstract

Keywords

agitoxin 2

Kv1.3 channel

pore blocker

fluorescent ligand

affinity

KcsA

hybrid channels