EventsThe 9th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-9-01514
This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 9th International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 2005
Citation
Christophe Gomy, Andreea R. Schmitzer, New Bis-Urea Cross-Linking Monomers as Effective Oxyanion Receptors, in Proceedings of The 9th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2005, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-9-01514
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New Bis-Urea Cross-Linking Monomers as Effective Oxyanion Receptors

Christophe Gomy 1
Andreea R. Schmitzer 1
1. Department of Chemistry, Université de Montréal, C.P. 6128 Succursale, Centre-ville, Montréal, Québec, H3C 3J7, Canada
Abstract
A library of new polymerizable functional cross-linking monomers designed for complexation with the oxyanionic moiety of the chemotherapeutic drug methotrexate (MTX). The 1H NMR binding study of a variety of synthetic receptors and the compilation of the obtained results lead to the identification of monomers combining interactive functionality and a cross-linking format, specific binding receptors for dicarboxylate-containing drugs.
Keywords
Synthesis and Biological Evaluation of Pyrazinecarboxamides
Synthesis and Dihydrofolate Reductase Inhibitory Activity of 2-amino-[1,3,5]triazino[1,2-a]benzimidazoles