Events The 27th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session S2. Bioorganic, Medicinal and Natural Products Chemistry of the event The 27th International Electronic Conference on Synthetic Organic Chemistry

Published date

15 Nov, 2023

Academic Editor

Julio A. Seijas

Citation

Santiago Stabile, Gabriel Radivoy, Facundo Chrestia, Cecilia Bouzat, <em>Design, Synthesis, and Biological Assessment of Novel Vanillin-Isoxazole Derivatives as Positive Allosteric Modulators of </em>α<em>7 Nicotinic Acetylcholine Receptor</em>, in Proceedings of The 27th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2023, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-27-16097

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Design, Synthesis, and Biological Assessment of Novel Vanillin-Isoxazole Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptor

Santiago Stabile ¹

Facundo Chrestia ²

Gabriel Radivoy ¹

Cecilia Bouzat ²

1. Instituto de Química del Sur, INQUISUR (CONICET-UNS), NANOSYN. Departamento de Química, Universidad Nacional del Sur, Avda. Alem 1253, 8000 Bahía Blanca, Argentina.

2. Departamento de Biologı́a, Bioquı́mica y Farmacia, Instituto de Investigaciones Bioquı́micas de Bahı́a Blanca (INIBIBB), Departamento de Biologı́a, Bioquı́mica y Farmacia, Universidad Nacional del Sur-Consejo Nacional de Investigaciones Cientı́ficas y Téc

Abstract

Keywords

nicotinic receptors

allosteric modulation

α7-PAM

isoxazoles