Events The 27th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session S2. Bioorganic, Medicinal and Natural Products Chemistry of the event The 27th International Electronic Conference on Synthetic Organic Chemistry

Published date

06 Dec, 2023

Academic Editor

Julio A. Seijas

Citation

Aleksey Dolganov, Alexandra Chikava, Victor Dotsenko, Reaction of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile with electrophilic agents , in Proceedings of The 27th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2023, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-27-16081

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Reaction of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile with electrophilic agents

Aleksey Dolganov ¹

Alexandra Chikava ¹

Victor Dotsenko ^2,3,4

1. Kuban state university, Russia

2. ChemEx Lab, Vladimir Dal’ Lugansk National University, Russia

3. Kuban state university

4. North Caucasus Federal University

Abstract

1,6-diamino-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile, prepared by the reaction of cyanoacetohydrazide with arylmethylene malononitriles, react with ninhydrin to give correspondingWith the formation of derivatives of dihydroindeno[1,2-e]pyrido[1,2-b][1,2,4]triazines. The reaction with glyoxal proceeds under mild conditions with the formation of 1,2,4-triazolo[1,5-a]pyridine.

Keywords

1,6-diaminopyridines

cyanoacethydrazide

malononitrile

Manuscript

sciforum-082016-clean.pdf

Multicomponent, Solvent‐free Synthesis of 4-substituted aminopyrido[2,3-d]pyrimidine derivatives

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