EventsThe 27th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-27-16251 (registering DOI)
This submission belongs to the session S1. General Organic Synthesis of the event The 27th International Electronic Conference on Synthetic Organic Chemistry
Published date
15 Nov, 2023
Academic Editor
author-avatarJulio A. Seijas
Citation
Regina Khayrullina, Catalytic aminomethylation of aliphatic and aromatic amines using (thio)urea, in Proceedings of The 27th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2023, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-27-16251
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Catalytic aminomethylation of aliphatic and aromatic amines using (thio)urea

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Regina Khayrullina 1
1. Institute of Petrochemistry and Catalysis of Russian Academy of Sciences, Russia
Abstract

To continue our research on catalytic aminomethylation, we studied the effect of catalysts on this reaction involving aliphatic and aromatic amines. We have developed an effective method for the production of cyclic and acyclic carbamide-containing compounds. It is based on the reaction between amines and 1,3-bis[dimethylamino(hydroxy)methyl](thio)urea, prepared in situ from urea or thiourea and bis(dimethylamino)methane or formaldehyde in the presence of NiCl2•6H2O, or CuCl2 •2H2O, and SmCl3•6H2O as catalysts.

Keywords
aminomethylation
cyclic and acyclic N-containing compounds
amines
catalyst
Manuscript
sciforum-081921-revised.pdf
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