EventsMOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Published
This submission belongs to the session 02. CHEMBIO.MOL-09: Org. Chem., Med. Chem., Mol. Biol., & Pharm. Industry Congress, Paris, France-Fargo, USA, 2023. of the event MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed.
Published date
23 Dec, 2023
Academic Editor
author-avatarHumbert G. Díaz
Citation
Ruzimurod Jurayev Sattorovich, Azimjon Uralivich Choriyev, Bekzod Ravshanovich Eshqulov, 2,3-dihydrobenzo[b][1,4]dioxine N-alkylation using various proton catalysts, in Proceedings of MOL2NET'23, Conference on Molecular, Biomed., Comput. & Network Science and Engineering, 9th ed., 25 December–31 December 2023, MDPI: Basel, Switzerland
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2,3-dihydrobenzo[b][1,4]dioxine N-alkylation using various proton catalysts

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1. Department of “Chemical Engineering and Quality Management”, Shakhrisabz Branch of Tashkent Institute of Chemical Technology, 20, Shahrisabz str., Shakhrisabz 181306, Uzbekistan, Uzbekistan
2. Karshi Statе University, Kuchabog street, 17, 180103, Karshi, Uzbekistan;, Uzbekistan
3. Shakhrisabz Branch of Tashkent Institute of Chemical Technology, 20, Shahrisabz str., Shakhrisabz 181306, Uzbekistan, Uzbekistan
Abstract

The majority of the compounds that are created using 2,3-dihydrobenzo[b][1,4]dioxine have pharmacological qualities and are employed as synthesis intermediates to create a variety of medications and medicinal substances that are used to treat different illnesses that affect the human body. Thus, the N-alkylation reaction between 2-(2-hydroxyethyl)isoindoline-1,3-dione and 2,3-dihydrobenzo[b][1,4]dioxine was examined in this study. It was investigated how different proton catalysts affected the N-alkylation process. The resulting compound's structure was examined by the application of physico-chemical study methods.

Keywords
proton catalyst
N-alkylation
spectrum analysis
2-(2-hydroxyethyl)isoindoline-1,3-dione
2,3-dihydrobenzo[b][1,4]dioxine
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