Events The 2nd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 2nd International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 1998

Citation

Martin Wills, Matthew Palmer, Athene Smith, Jennifer Kenny, Recent Developments in the Area of Asymmetric Transfer Hydrogenation., in Proceedings of The 2nd International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1998, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-2-01668

Facebook

Twitter

Recent Developments in the Area of Asymmetric Transfer Hydrogenation.

Martin Wills ¹

Matthew Palmer ¹

Athene Smith ¹

Jennifer Kenny ¹

1. Department of Chemistry, University of Warwick, Coventry, CV4 7AL.

Abstract

The use of an enantiomerically pure amino alcohol, coupled to a transfer hydrogenation process, in the asymmetric catalysis of the reduction of ketones to alcohols, is described. The process works well for unfunctionalised ketones, affording e.e.s of up to 98%, and excellent conversions. We have recently extended, for the first time in this application, the scope of the methodology to the reductions of a-heteroatom substituted substrates, through the use of the appropriate protecting groups on each atom.

Keywords

n/a

Biocatalytic Strategies for the Preparation of Chiral Building Blocks in 100% Chemical and Optical Yield from Racemates

Thermal Cyclization of 2-Hydrazonoacyl-3-oxo-heterocycles to Pyrazolo[4,3-c]fused Heterocycles