Events The 2nd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 2nd International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 1998

Citation

V. N. Yarovenko, F. M. Stoyanovich, O. Yu. Zolotarskaya, I. V. Zavarzin, M. M. Krayushkin, A new approach to synthesis of 2-carbamoylbenzothiazoles, in Proceedings of The 2nd International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1998, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-2-01678

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A new approach to synthesis of 2-carbamoylbenzothiazoles

V. N. Yarovenko ¹

F. M. Stoyanovich ¹

O. Yu. Zolotarskaya ¹

I. V. Zavarzin ¹

M. M. Krayushkin ¹

1. N.D.Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 117913 Moscow, Russian Federation.

Abstract

The reactions of substituted anilines with chloroacetamide and sulfur in the presence of triethylamine afford monothiooxamides, which being treated with K3Fe(CN)6 are cyclized to 2-carbamoylbenzothiazoles. The cyclization is established to be accompanied by the formation of the corresponding thiooxanilic acids, which are also cyclized to benzothiazole-2-carboxylic acids.

Keywords

Anilines

chloroacetamides

sulfur

monothiooxamides

2-carbamoylbenzothiazoles

thiooxanilic acids

benzothiazole-2-carboxylic acids.

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