EventsThe 2nd International Electronic Conference on Synthetic Organic Chemistry
Published
This submission belongs to the session b. Combinatorial Synthesis, Parallel Synthesis and Automation of the event The 2nd International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 1998
Citation
Árpád Furka, The "Portioning-Mixing" (Split-Mix) Synthesis, in Proceedings of The 2nd International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1998, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-2-01687
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The "Portioning-Mixing" (Split-Mix) Synthesis

Árpád Furka 1
1. Advanced ChemTech Inc. 5609 Fern Valley Road, Louisville, KY 40228, USA
Abstract
The portioning-mixing (PM) procedure is one of the earliest combinatorial synthetic methods. It was introduced 10 years ago, in 1988 [1]-[3]. This method exemplified the first time that it is possible to prepare with high confidence a previously unimaginable large number of compounds. It taught a large number of chemists to think combinatorially. The tenth anniversary of the method offers an occasion to summarize its main advantages, the areas of application and new developments.
Keywords
n/a
Polyalkoxy Nitrones as Chiral Building Blocks in Asymmetric Synthesis
Highly efficient and versatile Synthesis of Libraries of constrained b-strand Mimetics