EventsThe 3rd International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-3-01760
This submission belongs to the session b. Combinatorial Synthesis, Parallel Synthesis and Automation of the event The 3rd International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 1999
Citation
Bernd Renneberg, Werner Breitenstein, Coupling of Phenols to 2-Chlorotrityl Resins under Non-basic Conditions, in Proceedings of The 3rd International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1999, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-3-01760
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Coupling of Phenols to 2-Chlorotrityl Resins under Non-basic Conditions

Bernd Renneberg 1
Werner Breitenstein 2
1. Argonaut Technologies AG, P.O. Box 43, CH-4132 Muttenz 2, Switzerland
2. Combinatorial Chemistry Unit, Core Technology Area, Novartis Pharma Inc., CH-4002 Basel, Switzerland
Abstract
A new procedure for the coupling of phenols to 2-chlorotrityl resins has been developed using polymer bound 2-pyridyl ether derivative 1 as tritylation agent. The method allows the immobilisation of phenols under non-basic conditions and is particularly suited for base sensitive phenolic compounds. Scope and limitation of this new coupling method have been investigated.
Keywords
n/a
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