Events The 3rd International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session c. Medicinal and Bioorganic Application of Organic Synthesis of the event The 3rd International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 1999

Citation

Thanukrishnan Kannan, Subramaniam Vinodhkumar, Duraikkannu Loganathan, Synthesis of Glycosyl Phosphoramidates: Novel Isosteric Analogs of Glycosyl Phosphates, in Proceedings of The 3rd International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1999, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-3-01768

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Synthesis of Glycosyl Phosphoramidates: Novel Isosteric Analogs of Glycosyl Phosphates

Thanukrishnan Kannan ¹

Subramaniam Vinodhkumar ¹

Duraikkannu Loganathan ¹

1. Indian Institute of Technology Madras, Chennai-600 036, India

Abstract

Several glycosyl phosphoramidates, which are novel isosteric analogs of glycosyl phosphates, were synthesized in four steps starting from the free sugars, the key step being the Staudinger reaction of fully acetylated b -D-glycosyl azide with trimethyl phosphite.

Keywords

Glycosyl phosphoramidates

Isosteric analogs

Staudinger reaction.

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