EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01785
This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
Tommaso Mecca, Stefano Superchi, Carlo Rosini, Preparation of new enantiopure atropisomeric b-aminoalcohols and their use in asymmetric catalysis: enantioselective addition of diethylzinc to aromatic aldehydes., in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01785
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Preparation of new enantiopure atropisomeric b-aminoalcohols and their use in asymmetric catalysis: enantioselective addition of diethylzinc to aromatic aldehydes.

Tommaso Mecca 1
Stefano Superchi 1
Carlo Rosini 1
1. Dipartimento di Chimica, Università degli Studi della Basilicata, Via N. Sauro 85, 85100 Potenza, Italy.
Abstract
A new class of enantiopure b-aminoalcohols having 1,1’-binaphthyl skeleton, and chiral only by atropisomerism, has been prepared and tested as catalytic precursors in the asymmetric addition of diethylzinc to aromatic aldehydes. The aldehydes were quickly and cleanly (99% yield) transformed in the corresponding alcohols with ee up to 87%.
Keywords
b-aminoalcohols
atropisomerism
1,1’-binaphthyls
diethylzinc.
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