Events The 13th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 13th International Electronic Conference on Synthetic Organic Chemistry

Published date

31 Oct, 2009

Citation

Jozef Gonda, Miroslava Martinková, Kvetoslava Pomikalová, Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues, in Proceedings of The 13th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2009, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-13-00179

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Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues

Jozef Gonda ¹

Miroslava Martinková ¹

Kvetoslava Pomikalová ¹

1. Institute of Chemical Sciences, Department of Organic Chemistry, P. J. Šafárik University, Moyzesova 11, Košice, Slovak Republic

Abstract

An efficient strereocontrolled synthesis of substituted oxazolidin-2-one synthon 11 as the key intermediate in the synthesis of FTY720 analogues starting from the highly functionalized furanose scaffold 21 is reported.

Keywords

Substituted Pyridopyrimidinones. Part III. Synthesis of Some Novel Ether Derivatives of 4H-Pyrido[1,2-a]pyrimidin-4-one

Synthesis of N-substituted-3,4,5,6-tetrachlorophthalimide using trichloroacetimidate C-C bond formation method