Events The 4th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry

Published date

11 Sep, 2000

Citation

Montserrat Varea, Jose M. Sansao, Carmen Najera, Ana Costa, Jesus Casas, Diego Alonso, Tomas Abellan, (S)-5-(Tosylmethyl)-2-pyrrolidinone: A New Chiral b -Amidosulfone for a Short Asymmetric Synthesis of Indolizidines, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01811

Facebook

Twitter

(S)-5-(Tosylmethyl)-2-pyrrolidinone: A New Chiral b -Amidosulfone for a Short Asymmetric Synthesis of Indolizidines

Tomas Abellan ¹

Diego Alonso ¹

Jesus Casas ¹

Ana Costa ¹

Carmen Najera ¹

Jose M. Sansao ¹

Montserrat Varea ¹

1. Departamento de Quimica Organica, Universidad de Alicante. E-03080 Alicante, Spain

Abstract

The synthesis of (S)-5-(tosylmethyl)-2-pyrrolidinone from (S)-pyroglutaminol [(S)-2-(hydroxymethyl)-2-pyrrolidinone] in three steps and its applications into the synthesis of indolizidines is described in this communication.

Keywords

Asymmetric synthesis

Sulfones

Indolizidines

Dianions

Alkylation

1,3-Dipolar Cycloaddition Reactions with Azomethine Ylides Catalysed by Ag(I). Synthesis of Substituted Prolines

New Chiral Phase Transfer Supported Catalysts in The Asymmetric Synthesis of a -Amino Acids : The Importance of a Spacer