Events The 4th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry

Published date

11 Sep, 2000

Citation

Mario Orena, Giovanna Mobbili, Roberta Galeazzi, Christiana Fava, 4,5-Disubstituted Pyrrolidin-2-ones starting from D-Xylose, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01818

Facebook

Twitter

4,5-Disubstituted Pyrrolidin-2-ones starting from D-Xylose

Christiana Fava ¹

Roberta Galeazzi ¹

Giovanna Mobbili ¹

Mario Orena ¹

1. Dipartimento di Scienze dei Materiali e della Terra - Universita di Ancona Via Brecce Bianche I-60131 - Ancona, Italy

Abstract

Several non-proteinogenic amino acids containing the pyrrolidine ring show high affinity towards NMDA (N-methyl-D-aspartic acid) and glutamate receptors. Thus, they can be employed in order to establish the mechanisms involved in transmission of nerve impulse. Moreover, they can be used for treatmentment of CNS diseases. Among them, 2- carboxy-3-pyrrolidinacetic acid (CPAA), 1, and the diastereomeric 2-carboxy-4-(2-methoxyphenyl)-3- pyrrolidineacetic acids 2 and 3 are significant examples

Keywords

n/a

A Comparison of Two Effective Chiral Auxiliaries - (2R)-bornane-10,2-sultam and (2R)-bornane-10,2-cyclohydrazide - using the [4+2] Cycloaddition of Cyclopentadiene to their N,N'-fumaroyl derivatives

New Fluorous Chiral Phosphorous Ligands Based on the Binaphthyl Skeleton