Events The 4th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry

Published date

11 Sep, 2000

Citation

Sonia Pulacchini, Giovanna Pirri, Serenella Medici, Serafino Gladiali, Synthesis, Resolution and Use in Enantioselective Catalysis of an Axially Chiral Binaphthyl-templated P,S-heterodonor Ligand (binaps), in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01831

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Synthesis, Resolution and Use in Enantioselective Catalysis of an Axially Chiral Binaphthyl-templated P,S-heterodonor Ligand (binaps)

Serafino Gladiali ¹

Serenella Medici ¹

Giovanna Pirri ¹

Sonia Pulacchini ¹

1. Dipartimento di Chimica, Universite di Sassari, Via Vienna 2, 07100 Sassari (Italia

Abstract

The synthesis of racemic or enantiopure 2-diphenylphosphanyl-1,1'-binaphthalene-2'-thiol 8 (BINAPS) has been accomplished through a multistep reaction sequence from racemic or enantiopure binaphthol, respectively. The reaction sequence is completely stereoconservative. Enantiopure 8 can be alternatively obtained by resolution of rac-8 using the chiral benzylaminato Pd(II)-complex 16 as the resolving agent.

Keywords

Heterodonor ligands

Binaphthalene derivatives

Enantioselective catalysis

Transition metal catalysts

Allylic alkylation

Microwave-mediated Regioselective Synthesis of Novel Pyrimido[1,2-a]pyrimidines under Solvent-free Conditions

Towards a Selective Activation of Functional Groups Using Monochromatic Light