EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01855
This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
Roland U. Baum, Thomas J. J. Müller, A Coupling-Isomerization Sequence As An Entry To A Novel Three Component One-Pot Synthesis of 1,5-Benzoheteroazepines, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01855
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A Coupling-Isomerization Sequence As An Entry To A Novel Three Component One-Pot Synthesis of 1,5-Benzoheteroazepines

Thomas J. J. Müller 1
Roland U. Baum 1
1. Department Chemie, Ludwig-Maximilians-Universitat München, Butenandtstr. 5-13 (Haus F), D-81377 München, Germany
Abstract
2,4-Di(hetero)aryl substituted 2,3-dihydro 1,5-benzodiazepines, -oxazepines, and thiazepines can be readily synthesized in a three component one-pot process initiated by a coupling-isomerization sequence of an electron poor (hetero)aryl halide and a terminal propargyl alcohol subsequently followed by a cyclocondensation with 2-amino, 2-hydroxy, or 2-mercapto anilines.
Keywords
n/a
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