EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01865
This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
Stefan Bienz, Michael Trzoss, A Chiral Silyl Ether as Auxiliary for the Asymmetric Nucleophilic Addition to a- and b-Silyloxy Carbonyl Compounds, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01865
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A Chiral Silyl Ether as Auxiliary for the Asymmetric Nucleophilic Addition to a- and b-Silyloxy Carbonyl Compounds

Michael Trzoss 1
Stefan Bienz 1
1. Org.-chem. Institut, Universität Zürich, Winterthurerstrasse 190, 8057 Zürich
Abstract
Silyl ethers are well established protective groups in organic synthesis [1]. They are easily prepared and cleaved, and their reactivity can readily be controlled by the appropriate choice of the groups attached to silicon. In the course of our ongoing investigation of the chiral (tert-butyl)(methyl)(benzyloxymethyl)silyl group (I) as an auxiliary to control stereoselective processes [2] we got interested in the combined use of I as a protective and stereochemically directing group.
Keywords
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