EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01867
This submission belongs to the session a. General Organic Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
Robert Vleggaar, Thomas A. Logothetis, Synthesis of Homochiral R-(+)-2-Methyl-1-butanol, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01867
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Synthesis of Homochiral R-(+)-2-Methyl-1-butanol

Thomas A. Logothetis 1
Robert Vleggaar 1
1. Department of Chemistry, University of Pretoria, Pretoria 0002, South Africa
Abstract
R-(+)-2-Methylbutanol 10a, a building block of several natural products, is commercially unavailable. The total synthesis of 10a in four steps utilising the boronic ester homologation approach is described.
Keywords
boron
stereoselective synthesis
homologation
boronic esters
2-methylbutanol
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