EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01882
This submission belongs to the session b. Solid Phase Chemistry and Combinatorial Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
C. Oliver Kappe, Alexander Stadler, Solid Phase Coupling of Benzoic Acid to Wang Resin: A Comparison of Thermal Versus Microwave Heating., in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01882
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Solid Phase Coupling of Benzoic Acid to Wang Resin: A Comparison of Thermal Versus Microwave Heating.

Alexander Stadler 1
C. Oliver Kappe 1
1. Institute of Chemistry / Organic and Bioorganic Chemistry, Karl-Franzens-University Graz, A-8010 Graz, Austria.
Abstract
This presentation reports the possibility to carry out simple solid phase coupling reactions not only by conventional thermal heating but also by microwave dielectric heating. Thus coupling of benzoic acid to Wang resin occurs under microwave irradiation within 3 h in excellent yield (>99%) as compared to 72 h at room temperature. However, a further increase of reaction rates in this particular coupling reaction is not possible due to a side reaction that occurs at higher temperatures.
Keywords
n/a
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