EventsThe 4th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-4-01887
This submission belongs to the session b. Solid Phase Chemistry and Combinatorial Synthesis of the event The 4th International Electronic Conference on Synthetic Organic Chemistry
Published date
11 Sep, 2000
Citation
Henning Vogt, Matthias Lormann, Stefan Bräse, Scope and Limitation of a Tin Promoted Amidation on Solid Phase: A New Monitoring for the T1 Triazene Linker, in Proceedings of The 4th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2000, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-4-01887
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Scope and Limitation of a Tin Promoted Amidation on Solid Phase: A New Monitoring for the T1 Triazene Linker

Stefan Bräse 1
Matthias Lormann 1
Henning Vogt 1
1. RWTH Aachen, Institut für Organische Chemie, Professor-Pirlet-Str. 1, D-52074 Aachen, Germany
Abstract
The amidation of a benzoic acid derivative attached to solid support via the T1 triazene linkage has been described. In the presence of a tin amide reagent, smooth amidations take place with primary and secondary amines to give benzamides. Anilines failed under the reaction condition employed. The progress and the success of the reaction were monitored by 1H NMR spectroscopy using a novel direct cleaving method.
Keywords
n/a
One pot Synthesis of Propargylamines using Solid-Phase Extractive Isolation
A New Variant of the Baylis-Hillman Reaction for Solid Phase Organic Synthesis.