EventsThe 13th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-13-00191
This submission belongs to the session a. General Organic Synthesis of the event The 13th International Electronic Conference on Synthetic Organic Chemistry
Published date
31 Oct, 2009
Citation
Eugenio Uriarte, Lourdes Santana, Silvia Serra, Saleta Vázquez Rodríguez, Coumarin-Chalcone Hybrids as new scaffolds in drug discovery, in Proceedings of The 13th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2009, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-13-00191
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Coumarin-Chalcone Hybrids as new scaffolds in drug discovery

Eugenio Uriarte 1
Lourdes Santana 1
Silvia Serra 1
Saleta Vázquez Rodríguez 1
1. Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782, Spain
Abstract
The first hydroxilated series of coumarin-chalcone derivatives has been synthesize starting from the corresponding salicyl aldehyde and β-ketoester precursors by a Knoevenagel reaction in order to obtain the methoxy derivatives which have been further hydrolyzed with a Lewis acid.
Keywords
Coumarin
Chalcone
Knoevenagel
The crystal structure of a compartmental heptadentate ligand
Utilization of piperazine for interphase catalytic systems