Events The 8th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-8-01957

This submission belongs to the session a. General Organic Synthesis of the event The 8th International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 2004

Citation

Barbara Krassowska-Swiebocka, Grazyna Prokopienko, Lech Skulski, Aromatic Iodination Method with Iodic Acid Used as the Iodinating Reagent, in Proceedings of The 8th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2004, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-8-01957

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Aromatic Iodination Method with Iodic Acid Used as the Iodinating Reagent

Barbara Krassowska-Swiebocka ¹

Grazyna Prokopienko ¹

Lech Skulski ¹

1. Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Poland

Abstract

Benzene, halobenzenes, and a number of more or less deactivated arenes, including nitrobenzene, readily reacted in anhydrous HIO3/AcOH/Ac2O/concd H2SO4 mixtures to probably give ArIO2 intermediates or other hypervalent species (not isolated). The final reaction mixtures were poured into excess aq. Na2SO3 solution (a reductor) to give the purified iodinated products in 39-83% yields.

Keywords

arenes

iodoarenes

aromatic iodination

iodic acid as reactant and iodinating agent

Oxidative Iodination of Aromatic Amines and Other Arenes, with Sodium Percarbonate as the Oxidant

Oxidative Iodination of Various Deactivated Arenes with I2 or KI in Concentrated Sulfuric Acid, and with Sodium Periodate Added as the Oxidant