Events The 8th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-8-01974

This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 8th International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 2004

Citation

Klaus Gerdes, Shahzad Siddiqi, Jaywant Phopase, Ulrich Jordis, Synthesis of 7-(10, 11-Dihydro-5H-dibenzo[a,d]-cyclo-hepten-5-ylamino)-heptanoicacid (Amineptine), in Proceedings of The 8th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2004, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-8-01974

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Synthesis of 7-(10, 11-Dihydro-5H-dibenzo[a,d]-cyclo-hepten-5-ylamino)-heptanoicacid (Amineptine)

Klaus Gerdes ¹

Shahzad Siddiqi ¹

Jaywant Phopase ¹

Ulrich Jordis ¹

1. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163 1060 Vienna, Austria

Abstract

This paper discribes the improved synthesis of 7-(10, 11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylamino)-heptanoicacid (5) a synthetic, atypical tricyclic anti-depressant with central nervous system stimulating effects[1,2]. The synthesis was developed in context of the DrugMatrix[3] genomics project.

Keywords

n/a

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