Events The 8th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-8-01975

This submission belongs to the session c. Bioorganic Chemistry and Natural Products of the event The 8th International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Nov, 2004

Citation

Petr Knesl, Ulrich Jordis, Synthesis of Sulfapyridine Metabolites, in Proceedings of The 8th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2004, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-8-01975

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Synthesis of Sulfapyridine Metabolites

Petr Knesl ¹

Ulrich Jordis ¹

1. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria

Abstract

Sulfapyridine (SP) is an antibacterial compound that is used as such and also the active metabolite of sulfosalzazine (SASP) which shows antiphlogistic, antibacterial and immunomodulatoric properties. Sulfapyridine is also used to help control dermatitis herpetiformis (Duhring's disease), a skin problem. It has been reported, that sulfapyridine is metabolized to 5-hydroxysulfapyridine but no synthesis of this proposed metabolite has been published.We will report on the synthesis of thia and other potential metabolites of sulfapyridine.

Keywords

n/a

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