This submission belongs to the session e. Symposium on Microwave Assisted Synthesis of the event The 8th International Electronic Conference on Synthetic Organic Chemistry
Published date
01 Nov, 2004
Citation
Jaroslav Skubak, Behrooz H. Yousefi, Kishor More, Shahzad A. Siddiqi, Doris Domin, Jaywant Phopase, Ulrich Jordis, Microwave Assisted and Conventional Mono Aryl Substitution of Diazabicycloalkanes by Palladium Coupling, in Proceedings of The 8th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2004, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-8-01990
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Microwave Assisted and Conventional Mono Aryl Substitution of Diazabicycloalkanes by Palladium Coupling
Jaroslav Skubak 1
Behrooz H. Yousefi 1
Kishor More 1
Shahzad A. Siddiqi 1
Doris Domin 1
Jaywant Phopase 1
Ulrich Jordis 1
1. Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9, 1060 Vienna, Austria
Abstract
The typical synthetic routes to the mono-aryl substituted piperazines are palladium catalyzed C-N coupling of piperazine or protected piperazines with aryl halides. In this work we describe the synthesis of aryl piperazines and aryl diazabicycles utilizing Pd catalyzed coupling reactions using protected and unprotected piperazines and diazobicycles performed both conventionally and by microwave assisted organic synthesis (MAOS).
Keywords
n/a
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