EventsThe 2nd International Electronic Conference on Clinical Medicine
Published
This submission belongs to the session S3. Epidemiology & Public Health of the event The 2nd International Electronic Conference on Clinical Medicine
Published date
11 Nov, 2024
Academic Editor
author-avatarFrancisco Guillen-Grima
Citation
Georgia Petra, Evangelos Kritsotakis, Stamatios Kokkinakis, Aikaterini Rasouli, Alexandros Tsiavos, John Tsikritzakis, Giorgos Papadakis, Konstantina Raouzaiou, Dimitrios Schizas, Athanasios Syllaios, Markos Despotidis, Adam Mylonakis, Panagiotis Dorovinis, Nikolaos Machairas, Mytro Keramida, Stylianos Kykalos, Konstantinos Toutouzas, Maximos Frountzas, Dimosthenis Sotirakis, Michael Karanikas, Konstantinia Kofina, Eleni Efremidou, Markos Markou, Rodoula Sotiropoulou, Michael Pitiakoudis, Georgios Pappas-Gogos, Christos Tsalikides, Anastasios Karayiannakis, Aggelos Laliotis, Ifigenia Tzartzalou, Ioannis Gkionis, Ioannis Kechagias, Dimitrios Kehagias, Georgios Ioannis Verras, Georgios Stylianidis, Georgios Giannos, Georgios Zacharioudakis1, Savvas Tsaramanidis, Antonios Morsi-Yeroyannis, Nikolaos Gouvas, Kyriaki Konstantinou, Panayiotis Papatheodorou, Andia Stylianou, Despo Evripidou, Grigorios Christodoulidis, Garyfallia Apostolia Karali, Emmanuel Chrysos, Konstantinos Lasithiotakis, SURGICAL SITE INFECTIONS AFTER MAJOR ABDOMINAL SURGERY IN GREECE: RESULTS OF A NATIONWIDE MULTICENTRE STUDY, in Proceedings of The 2nd International Electronic Conference on Clinical Medicine, 13 November–15 November 2024, MDPI: Basel, Switzerland
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SURGICAL SITE INFECTIONS AFTER MAJOR ABDOMINAL SURGERY IN GREECE: RESULTS OF A NATIONWIDE MULTICENTRE STUDY

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Aikaterini Rasouli 1
John Tsikritzakis 1
Giorgos Papadakis 1
Konstantina Raouzaiou 1
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Markos Markou 5
Rodoula Sotiropoulou 5
Michael Pitiakoudis 6
Ifigenia Tzartzalou 7
Ioannis Gkionis 7
Ioannis Kechagias 8
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Georgios Zacharioudakis1 10
Savvas Tsaramanidis 10
Antonios Morsi-Yeroyannis 10
Andia Stylianou 11
Despo Evripidou 11
Garyfallia Apostolia Karali 12
Emmanuel Chrysos 1
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1. Department of General Surgery, School of Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece, Greece
2. Laboratory of Biostatistics, School of Medicine, University of Crete, Heraklion, Crete, Greece, Greece
3. First Propaedeutic Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece, Greece
4. First Department of Surgery, Hippokrateio Hospital , National and Kapodistrian University of Athens, Athens, Greece, Greece
5. First Department of Surgery, School of Medicine, University General Hospital of Alexandroupolis, University of Thrace, Alexandroupolis, Greece, Greece
6. Second Department of Surgery, School of Medicine, University General Hospital of Alexandroupolis, University of Thrace, Alexandroupolis, Greece, Greece
7. Venizeleio Hospital, Department of Surgery, Heraklion, Crete, Greece, Greece
8. Department of Surgery, School of Medicine, University General Hospital of Patras, University of Patras, Patras, Greece, Greece
9. Second Department of Surgery, Evangelismos General Hospital, Athens, Greece, Greece
10. Department of Surgery, School of Medicine, Ippokrateio General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece, Greece
11. Department of Surgery, School of Medicine, General Hospital of Nicosia, University of Cyprus, Nicosia, Cyprus, Cyprus
12. Department of Surgery, University of Thessaly, Thessaly, Greece, Greece
Abstract

Background: Surgical site infections are a major cause of postoperative morbidity and mortality, but data regarding their prevalence in Greece are scarce. In this study, we report the rates of surgical site infections after major abdominal surgery in a large sample of patients in Greece.

Methods: This was a prospective multicentre trial (NCT 05393752) including 11 tertiary hospitals from Greece and Cyprus. Patients undergoing major/major+ abdominal surgery during 2022-2023 were included. Surgical site infections were classified according to the definitions of the CDC, and for sepsis, the SEPSIS-3 criteria were used. Demographics, type/site/magnitude of the operation, American Society of Anesthesiologists class, and the presence/stage of malignancy, as well as comorbidities, were recorded.

Results: There were 1649 patients (41,8% females) with a mean age of 66.3 years (SD: 13.8). The most common site of operation was the lower GI tract (58,9%), followed by the upper GI tract (20.2%) and the hepatobiliary system (13.6%). A total of 30.6% of the operations were performed on an emergency basis, and 3% of the patients had sepsis/shock. The rates of smoking, COPD, diabetes, corticosteroid use, and chronic renal failure were 23.5%, 9.7%, 22%, 6.5%, and 0,8%, respectively. Cancer diagnosis was present in 68.2% of patients and distant metastases in 9.7%. Postoperatively, 7.5% of patients developed sepsis and 3.3% developed septic shock. A total of 322 SSIs were recorded (19.8%), of which 13.3% were superficial, 2.7% deep, and 3.5% were in the organ space. SSIs were significantly more common in emergency operations, in hepatobiliary sites, and in patients with cancer (p<0.01).

Conclusion: SSIs are common after major abdominal surgery, even though most of them are superficial. At relatively high risk are hepatobiliary, oncological, and urgent operations.

Keywords
surgical site infections
major surgery
gastrointestinal operations
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