Events The 1st International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

10.3390/ecsoc-1-02026

This submission belongs to the session a. General Organic Synthesis of the event The 1st International Electronic Conference on Synthetic Organic Chemistry

Published date

01 Sep, 1997

Citation

Elliad R. Silcoff, Tuvia Sheradsky, The Synthesis of (2R,5R)-2-Amino-5-Hydroxyhexanoic Acid by Intermolecular Cycloaddition, in Proceedings of The 1st International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 1997, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-1-02026

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The Synthesis of (2R,5R)-2-Amino-5-Hydroxyhexanoic Acid by Intermolecular Cycloaddition

Tuvia Sheradsky ¹

Elliad R. Silcoff ¹

1. The Hebrew University Jerusalem, 91904 Israel

Abstract

The enantioselective synthesis of alpha amino acids which contain an additional chiral center at a remote position presents an important and complex synthetic problem. We have previously described the employment of a hetero Diels-Alder reaction for this purpose.1 In this project this methodology was notably extended, as demonstrated by the short synthesis of (2R,5R)-2-amino-4-hydroxyhexanoic acid.

Keywords

n/a

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